Colorectal cancer is swiftly shifting to more advanced disease and younger individuals according to Colorectal Cancer Statistics 2023, a new report on cancer facts and trends by the American Cancer Society (ACS). Researchers showed the proportion of individuals in the United States diagnosed with advanced-stage colorectal cancer increased from 52% in the mid-2000s to 60% in 2019. In addition, diagnoses of people under 55 years of age doubled from 11% (1 in 10) in 1995 to 20% (1 in 5) in 2019. Overall, in 2023, an estimated 153,020 people will be diagnosed with colorectal cancer in the U.S., and 52,550 people will die from the disease. These major findings are to be published today in CA: A Cancer Journal for Clinicians, alongside its consumer-friendly companion, Colorectal Cancer Facts & Figures 2023-2025, available on cancer.org. My guest is Dr. Arif Kamal, Chief Patient Officer, American Cancer Society.