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by all means一定；务必
by any means无论如何
by no means绝不
By all means,I must visit my sick friend.
我一定要探望我生病的朋友。
You must get there by all means before dark.
你们一定在天黑之前到达那里.
A:Could I borrow your pen,please?
我可以借用你的钢笔吗？
B:By all means.
当然可以。
背景音乐：soulchef-drafting in a daydream
