Simonetta Vespucci was the face that defined beauty in Renaissance Florence. Admired by the powerful Medici family and immortalised in Botticelli’s paintings, she seemed untouchable. But in 1476, at just 22 years old, Simonetta died suddenly. Officially, it was illness, but rumours of jealousy, poison, and political plots have surrounded her death ever since. In this episode, we explore the mystery behind the life and untimely end of Florence’s most famous muse.