I sit down with Jason Wright, and talk about Lynch Syndrome and gynecological cancers. Columbia's clinical program is a comprehensive center for hereditary abnormalities, including BRCA, Lynch and others. Obviously the goal is to identify those with a variant before they have cancer. There's still a greater awareness of BRCA, even before the Angelina effect. We talk about screening fatigue that can set in over time when you haven't had cancer for a considerable period of time, but you need to remain diligent. We are convinced that healthcare is the only sector still using fax machines. Cascade testing is still the best way of impacting hereditary cancer syndromes like Lynch. Columbia is working on mathematically modeling based around the specific gene mutation to strategize screening practices and mitigation options.