In this high-yield episode of Master USMLE, we break down mixed cryoglobulinemia syndrome (MCS)—a small-vessel vasculitis strongly linked to chronic hepatitis C infection. Learn the classic triad (palpable purpura, glomerulonephritis, neuropathy), key lab findings, and the best next step in diagnosis. Plus, we give you exam tips on how to differentiate vasculitides based on complement levels, ANCA status, and systemic involvement. Don’t miss this high-yield breakdown—it could be the difference between a right and wrong answer on test day!
