In this episode of OSCE Talk, we break down methotrexate — a high-risk but commonly prescribed DMARD used in conditions such as rheumatoid arthritis, psoriatic arthritis, and Crohn’s disease.
We explain:
how methotrexate works
why it is taken once weekly (and never daily)
the role of folic acid
key side effects, drug interactions, and monitoring
important counselling points around infection risk, pregnancy, and safety-netting
Clear, practical explanations you can use on the ward, in clinic, and in exams.