In this episode of The Feldman Protocol, special guest Mike Mutzel explores groundbreaking research on the immune system, GLP-1, the gut microbiome and lean mass hyper-responders. They deep dive on the Lipid Energy Model, atherosclerosis mechanisms, immune system interactions, coronary artery imaging data, and conventional cardiovascular risk paradigms in metabolic health.
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⏱ Chapters
3:01 – Introduction and Mike's background
9:14 – Medicine and nutrition evolution
17:44 – Mindful eating and GLP-1 connections
25:00 – Dave's cholesterol discovery story
31:42 – Understanding lipid trafficking physics
40:18 – Endothelial dysfunction and inflammation
49:00 – LDL oxidation and modification theories
58:23 – Atherosclerosis as immune response
1:05:47 – Blood viscosity and cardiovascular risk
1:15:19 – Self-censorship in scientific discourse
1:25:33 – Continual exposure hypothesis debate
1:32:19 – Own Your Labs citizen science project
1:40:58 – Cholesterol paradox in aging populations
1:50:33 – Metabolic health vs inflammation
2:00:12 – Radiation concerns with CT angiograms
2:08:56 – Triglycerides and ketogenic metabolism
2:18:47 – Study results and mainstream response
2:22:41 – Final thoughts and future research
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