In this episode of Beyond the Bedside, we break down Chapter 40: Oxygenation and Perfusion into clear, clinical, NCLEX-ready language. We walk through respiratory assessment and pulse oximetry (including what makes readings inaccurate), oxygen delivery systems from nasal cannula to nonrebreather masks, and safe skin and device management. You’ll get a bedside-focused tour of endotracheal tubes and tracheostomies, including cuff pressure management, communication strategies, emergency prep, and prevention of pressure injuries and infection. We go step-by-step through oro/nasopharyngeal and tracheal suctioning using open technique, then cover mechanical ventilation basics, manual resuscitation bags, choking relief, CPR, and AED use at the nursing student level. Using the evolving COPD case of Joan McIntyre, you’ll practice clinical reasoning, prioritize care, and finish with NCLEX-style questions and full rationales so you can walk into clinicals confident managing airways, oxygenation, and breathing support.