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It’s episode 117 and the only thing sinister about the Sinister Sisters is their luck. Cue the circus music! In today’s episode, Sarah covers the 12th leading cause of death in the United States - major depressive disorder - which doesn’t occur due to one life event. Specific symptoms have to be present for two weeks before it can be diagnosed. Sarah then dives into treatment options  but pulls the rug out from under us when she divulges a recent study's findings that depression may not actually be linked to a chemical imbalance. Now’s the time to down your Dr. Pepper.

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If you want to look into these topics yourselves, below are the sources used: (https://www.nimh.nih.gov/health/topics/depression);(https://www.nimh.nih.gov/health/topics/depression);(https://www.nature.com/articles/s41380-022-01661-0.pdf);(https://www.psychologytoday.com/us/blog/side-effects/202207/decisive-blow-the-serotonin-hypothesis-depression);(https://www.psychiatrictimes.com/view/debunking-two-chemical-imbalance-myths-again)