“My people are destroyed for lack of knowledge: because thou hast rejected knowledge, I will also reject thee, that thou shalt be no priest to me: seeing thou hast forgotten the law of thy God, I will also forget thy children (Hosea 4:6).”
The part ‘my people are destroyed for lack of knowledge‘ is popularly translated as ‘my people perish for lack of knowledge’. Hosea 4:6 means the same as it reads. Ignorance or lack of knowledge is one such destructive state. Many lives have been lost, many cruel deeds have been done, and many souls have perished on account of lack of knowledge. But God never wanted it to be so that is why He gave us his word.