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Talk Hashimoto's and fertility, might have to try to keep this one short, because I could go off on this one for a long, long time. I'm not going to get into the chemical pathways and things of that nature, but Hashimoto's does affect fertility. One of the biggest things that one of the biggest connections in fertility, I think with Hashimoto's is it has a connection to polycystic ovarian syndrome. They've done studies on young gals who are 12, 11, 13, 14 years old and who had cysts and they gave them thyroid medication and their cysts went away. So again, when I said, I have to keep this real, like, not go through all the chemical pathways, there are pathways that involve the adrenal glands and blood sugar manipulation that are secondary to Hashimoto's. Ultimately create these cysts people get polycystic ovarian disease probably understand, or those of you who don't know, is the cause of some studies estimate 50% of the infertility in this country.
That's a big crosstalk connection between the thyroid and the ovaries, but just in general, Hashimoto's thyroiditis is a hypo thyroid condition. Hypothyroid conditions slow everything down, it just slows everything down. It slows down your ability to make eggs, it slows down your ability to pop those eggs out. You can't get the egg out, no cycle, no baby. Hashimoto's works at it from that perspective. I have a lot of women who come in here and they're on hormone replacement therapy for their estrogen, and all of a sudden their thyroid starts getting better. They have to go down on their hormone replacement therapy because now they're starting to make more estrogen and they're making too much, and they're getting all kinds of symptoms of too much estrogen or getting heavy periods and stuff like that.
It has a direct effect on estrogen metabolism. It has a direct effect on progesterone metabolism now in a little different way. Estrogen, you know, you make the egg, you have the baby, or you've already made the, heck you came with the eggs but you made it so that it can be expelled. The follicle can become that you can get into the uterus, that's estrogen. Estrogen does all that, but progesterone makes the uterus so that the follicle will stick so that it will hold. Progesterone has a very interesting relationship with the thyroid hormone. Thyroid hormone will sensitize the receptor sites on the cells so that the progesterone gets in there better. If you have hypo thyroid, and you're not producing enough thyroid hormone, or you're not converting enough thyroid hormone from T4 to T3, then you're not going to have your thyroid hormone sensitizing the progesterone.
Maybe you can see, but then you can't carry to term and you have miscarriages and women who have hypothyroidism and Hashimoto's type with thyroid ism, I think are four times more likely to miscarry. Another thing relative to thyroid hormone is when thyroid hormone decreases, high thyroid hormone is under the auspices of your pituitary glands. Your pituitary glands tells your thyroid what to do and so they have a very close relationship. When we get a decreased hypo thyroid ism, particularly the most common one, which is Hashimoto's, inflammation can affect that pituitary gland.
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