What is a nicotine salt? Nicotine salts, also known as nic salts are chemical substances extracted from tobacco leaves. Nicotine salt juices are e-liquids prepared using nic salts. Nic salt e-liquids are nothing new, people have been using them for quite some time. But it was until recently when you can find a wide variety of tasty and satisfying nic salt e-liquids in the market. Here are the the best nic salt juices in 2020.