Drs. Ron Waksman and Pierre Amarenco discuss a subgroup analysis of the THALES study, which was presented at the American Heart Association Scientific Sessions 2020 virtual conference. This analysis showed that ticagrelor added to aspirin reduced the 30-day risk of recurrent stroke by 27% in transient ischemic attack (TIA) and minor ischemic stroke patients with ipsilateral atherosclerotic stenosis of cervicocranial vasculature.