This is an example of a fast that lasted over a year and resulted in a weight loss of 277 pounds. It occurred in 1965, and a subsequent clinical paper was written. This gives us an idea as to what happens metabolically when you fast for long periods of time. This is a therapeutic fast and should be considered a last resort. Also unlike our short fasts, you need to see a health care provider. If you are considering a gastric bypass, perhaps you should check this out. There will be fewer side effects, it will be cheaper, and the weight loss will probably last longer.