In this episode, we will talk about the reason SARS-COV2 has appeared to be deadlier than its predecessor SARS-COV1 and the lower risk of COVID-19 disease in asthma patients. Next, the effect of wildfires on the intensity of storms and magnetic pole shifting 42000 years ago will be described. Finally, the mechanism of improved immunity as a result of exercise, a new compound to treat ALS and the negative effect of fructose will be overviewed.
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The papers reviewed in this podcast:
1. Anthony P Sunjaya, Sabine M Allida, Gian Luca Di Tanna, Christine Jenkins. Asthma and risk of infection, hospitalisation, ICU admission and mortality from COVID-19: Systematic review and meta-analysis. Journal of Asthma, 2021; 1 DOI: 10.1080/02770903.2021.1888116
2. Lydia G. Jahl, Thomas A. Brubaker, Michael J. Polen, Leif G. Jahn, Kerrigan P. Cain, Bailey B. Bowers, William D. Fahy, Sara Graves, Ryan C. Sullivan. Atmospheric aging enhances the ice nucleation ability of biomass-burning aerosol. Science Advances, 2021; 7 (9): eabd3440 DOI: 10.1126/sciadv.abd3440
3. Alan Cooper, Chris S. M. Turney, Jonathan Palmer, Alan Hogg, Matt Mcglone, Janet Wilmshurst, Andrew M. Lorrey, Timothy J. Heaton, James M. Russell, Ken Mccracken, Julien G. Anet, Eugene Rozanov, Marina Friedel, Ivo Suter, Thomas Peter, Raimund Muscheler, Florian Adolphi, Anthony Dosseto, J. Tyler Faith, Pavla Fenwick, Christopher J. Fogwill, Konrad Hughen, Mathew Lipson, Jiabo Liu, Norbert Nowaczyk, Eleanor Rainsley, Christopher Bronk Ramsey, Paolo Sebastianelli, Yassine Souilmi, Janelle Stevenson, Zoë Thomas, Raymond Tobler, Roland Zech. A global environmental crisis 42,000 years ago. Science, 2021 DOI: 10.1126/science.abb8677
4. Bo Shen, Alpaslan Tasdogan, Jessalyn M. Ubellacker, Jingzhu Zhang, Elena D. Nosyreva, Liming Du, Malea M. Murphy, Shuiqing Hu, Yating Yi, Nergis Kara, Xin Liu, Shay Guela, Yuemeng Jia, Vijayashree Ramesh, Claire Embree, Evann C. Mitchell, Yunduo C. Zhao, Lining A. Ju, Zhao Hu, Genevieve M. Crane, Zhiyu Zhao, Ruhma Syeda, Sean J. Morrison. A mechanosensitive peri-arteriolar niche for osteogenesis and lymphopoiesis. Nature, 2021; DOI: 10.1038/s41586-021-03298-5
5. Barış Genç, Mukesh Gautam, Öge Gözütok, Ina Dervishi, Santana Sanchez, Gashaw M. Goshu, Nuran Koçak, Edward Xie, Richard B. Silverman, P. Hande Özdinler. Improving mitochondria and ER stability helps eliminate upper motor neuron degeneration that occurs due to mSOD1 toxicity and TDP‐43 pathology. Clinical and Translational Medicine, 2021; 11 (2) DOI: 10.1002/ctm2.336
6. Nicholas Jones, Julianna Blagih, Fabio Zani, April Rees, David G. Hill, Benjamin J. Jenkins, Caroline J. Bull, Diana Moreira, Azari I. M. Bantan, James G. Cronin, Daniele Avancini, Gareth W. Jones, David K. Finlay, Karen H. Vousden, Emma E. Vincent, Catherine A. Thornton. Fructose reprogrammes glutamine-dependent oxidative metabolism to support LPS-induced inflammation. Nature Communications, 2021; 12 (1) DOI: 10.1038/s41467-021-21461-4
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Music: https://www.purple-planet.com
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