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Proverbs 13:12

Hope deferred makes the heart sick,
    but a longing fulfilled is a tree of life.

To defer means to delay or postpone something. Therefore 'hope deferred' means hope delayed or hope postponed. From this explanation, we can now understand the context verse better. Therefore 'Hope deferred makes the hear sick' means that once you've put your hope on someone and they delay to make good on what they said, you will lose heart.