The same God who had made Paul the apostle of the Gentiles (v. 1) had also pressed the Roman Christians into the service of His imminent and coming Kingdom. As men called unto holiness, they belong no longer to themselves or to the old world which is passing to corruption. They belong to Him who has called them. Not for Paul only, but for them also, has the Son of man been appointed Son of God through the power of the Resurrection. They too are here and now imprisoned in the knowledge of great tribulation and of great hope. They too after their fashion are separated and isolated for God.