Even though we are sinners, Christ died for us. Even though we were dead in our trespasses and sins, God made us alive. Even though we had deserved death and damnation, God has condemned Jesus in our place and given us the glory he deserves.
You may be in a place of despair, distress, hopelessness, shame, disease, or death. But God has an abundance of grace, hope, life, healing, peace, and joy. He gives that to us by his grace. We may face grave and insurmountable challenges. But God's promises are fulfilled in Jesus, and gives them to us through faith.