Now, let's break down the Krebs cycle into its key stages and highlight the main reactions that take place:
Acetyl-CoA Formation:
The cycle begins when a two-carbon molecule called acetyl-CoA combines with a four-carbon molecule called oxaloacetate, forming a six-carbon molecule known as citrate. This step is catalyzed by the enzyme citrate synthase.
Citrate Isomerization:
The citrate molecule then undergoes a series of rearrangements, resulting in its isomerization into isocitrate. This conversion is facilitated by the enzyme aconitase.
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