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Past, present and future of therapeutic hypothermia.

Targeted temperature management (TTM) or Therapeutic hypothermia is recommended for patients after cardiac arrest, but the supporting evidence is of low certainty.
TTM-2 trial was recently published in NEJM (June 2021).
The TTM-2 trial tried to answer the question if Therapeutic hypothermia is any better than normal temperature in patients who are in coma after being resuscitated from cardiac arrest.
I have briefly discussed the trial, also touching briefly the recent and upcoming trials of hypothermia protocol.

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