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El ácido ursólico es una molécula que se encuentra en las cáscaras de manzana y en la hierba ayurvédica... si quieres saber como afecta tus músculo, grasa y mas... dale play


Referencias


1. Ursolic acid stimulates lipolysis in primary-cultured rat adipocytes. 


2. Kim J, et al. Anti-lipase and lipolytic activities of ursolic acid isolated from the roots of Actinidia arguta. Arch Pharm Res. (2009) 


3. Jang DS, et al. A new pancreatic lipase inhibitor isolated from the roots of Actinidia arguta. Arch Pharm Res. (2008) 


4. Ursolic Acid, A Pentacyclic Triterpene from Sambucus australis, Prevents Abdominal Adiposity in Mice Fed a High-Fat Diet. 


5. Boström P1, et al. A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis. Nature. (2012) 


6. Kunkel SD1, et al. Ursolic acid increases skeletal muscle and brown fat and decreases diet-induced obesity, glucose intolerance and fatty liver disease. PLoS One. (2012) 


7. Huh JY1, et al. Irisin stimulates muscle growth-related genes and regulates adipocyte differentiation and metabolism in humans. Int J Obes (Lond). (2014) 


8. Bang HS1, et al. Ursolic Acid-induced elevation of serum irisin augments muscle strength during resistance training in men. Korean J Physiol Pharmacol. (2014) 


9. Ung SH, et al. Insulin-mimetic and insulin-sensitizing activities of a pentacyclic triterpenoid insulin receptor activator. Biochem J. (2007) 


10. Kunkel SD, et al. mRNA expression signatures of human skeletal muscle atrophy identify a natural compound that increases muscle mass. Cell Metab. (2011) 


11. Ali H, Houghton PJ, Soumyanath A. alpha-Amylase inhibitory activity of some Malaysian plants used to treat diabetes; with particular reference to Phyllanthus amarus. J Ethnopharmacol. (2006) 


12. Sundaresan A, Harini R, Pugalendi KV. Ursolic acid and rosiglitazone combination alleviates metabolic syndrome in high fat diet fed C57BL/6J mice. Gen Physiol Biophys. (2012) 


13. a b c d Jang SM, et al. Inhibitory effects of ursolic acid on hepatic polyol pathway and glucose production in streptozotocin-induced diabetic mice. Metabolism. (2010) 


14. Lee EH, et al. Inhibitory effect of ursolic acid derivatives on recombinant human aldose reductase. Bioorg Khim. (2011) 


15. Zhou Y, et al. Ursolic acid inhibits early lesions of diabetic nephropathy. Int J Mol Med. (2010) 


16. Lee J, et al. Ursolic acid ameliorates thymic atrophy and hyperglycemia in streptozotocin-nicotinamide-induced diabetic mice. Chem Biol Interact. (2010) 


17. Li D, et al. Effects of ursolic acid on c-Cbl-associated protein expression in 3T3-L1 adipocytes with insulin resistance. Zhong Xi Yi Jie He Xue Bao. (2012)