Description

Description 

Why do we age? This episode explores the molecular processes of aging, and how they are related to the aging we can see. We ask what is aging and how we could slow or reverse it according to the most recent research.

Main References and Further Reading:

David Sinclair – Lifespan

Andrew Steele – Ageless

Lopez-Otin et al – The Hallmarks of Aging

Borghesan et al – A Senescence-Centric View of Aging: Implications for Longevity and Disease

Zhang et al - Senolytic therapy alleviates Aβ-associated oligodendrocyte progenitor cell senescence and cognitive deficits in an Alzheimer’s disease model

Mammucari et al - Signaling pathways in mitochondrial dysfunction and aging

Lu et al - Reprogramming to recover youthful epigenetic information and restore vision

Kane et al - Epigenetic changes during aging and their reprogramming potential

Kaushik et al - Proteostasis and Aging