Ian Maze is a Howard Hughes Medical Institute Investigator and Professor of Neuroscience and Pharmacological Sciences at the Icahn School of Medicine at Mount Sinai. His research involves studying the chromatin-based mechanisms of adult cognitive and psychiatric disorders like addiction and major depression, in particular how monoamines like serotonin and dopamine can act as epigenetic regulators to influence gene expression, and the implications in disease and treatment.
TIMESTAMPS
(00:42) – Epigenetics
(15:20) – Serotonin and depression
(18:42) – Serotonylation
(36:20) – Depression and epigenetics
(40:12) – Dopaminylation
(42:20) – Studying epigenetics of psychiatric disorders
(48:48) – Future of depression diagnosis and treatment
(51:40) – Ian’s academic journey
(57:00) – Advice for young scientists
