Listen

Description

Lisa Monteggia is the Barlow Family Director of the Vanderbilt Brain Institute and Professor of Pharmacology at Vanderbilt University. Her research focuses on the molecular and cellular mechanisms underlying psychiatric disorders like depression, uncovering the mechanisms by which traditional antidepressants like SSRIs exert their antidepressant response and uncovering how exactly more recent antidepressants like ketamine are able to produce an antidepressant response so quickly.

TIMESTAMPS

(00:43) – Depression

(02:22) – History of depression

(07:25) – Causes of depression

(15:11) – SSRIs and neurotrophins

(23:33) – Ketamine

(45:30) – Does ketamine fix underlying pathophysiologies?

(59:02) – Experimental challenges

(1:00:36) – Psychopharmacology

(1:02:13) – Advice for young scientists