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What are the molecular hallmarks of lipedema? That question was the focus of the September Research Roundtable with Dr. Leon Straub, whose recent research paper identified key molecular features of the disease. The study, “Defining lipedema’s molecular hallmarks by multi-omics approach for disease prediction in women,” was funded by the Lipedema Foundation, and Dr. Karen Herbst contributed as a corresponding author.

During this in-depth discussion, Drs. Straub and Herbst explored a breadth of topics, including the stages of lipedema, brown fat, macrophages, inflammation, mitochondria, the impact of menopause, and how lipedema disrupts correlations between serum adipokines and BMI.

Dr. Straub earned his M.S. in Life and Medical Sciences from the University of Bonn and completed his doctorate at ETH Zurich, where he studied how adipose tissue insulin resistance influences diabetes development. He is currently a guest scientist at University Medical Center Hamburg-Eppendorf.

This Roundtable was originally recorded live on September 8, 2025. The views and opinions expressed in this program are those of the speakers and do not necessarily reflect the opinions or positions of Lympha Press. The content is for educational purposes only and not intended as medical advice.

Watch more Roundtables from our Lympha Press Research Roundtables playlist on YouTube.