One little change, after a series of spectacular mistakes, because he is Loki, and now the Asgardian refugee vessel makes it to Earth in one piece. Now that Earth has Thor, Loki wrestles with how helpful he really needs to be in this whole defeating Thanos thing. He did his part, right? Now he would much rather spend his time causing mischief (with minimal property damage and no permanent physical harm, because Thor made him promise). Also, finding ways to put a certain Billionaire, Genius, Playboy, Philanthropist out of his mind or to possibly get in his pants, he isn't quite sure yet.
