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Oprah Winfrey has transitioned The Oprah Winfrey Show, which ran for 25 years, into a media and business empire. The former news anchor built the reinvested profits from her talk show into $2 billion, according to "Forbes" estimates.

In 2011, Winfrey launched cable channel OWN. Her 25.5% of the network is worth more than $65 million. The 'Oprah effect' has spread to Weight Watchers: she bought a 10% stake in 2015 (since lowered to 7%) and acts as a brand ambassador. In March 2020, she returned to the small screen on Apple TV+ for an interview show about Covid-19 as part of her multiyear pact with the streamer.