This week on the Sagecast we are joined by Professor of Chemistry Jane Liu. Liu studies the role of functional RNAs (such as catalytic and regulatory RNAs) in controlling the dynamic aspects of gene expression in response to a changing environment. She seeks to apply this knowledge to the development of novel tools for chemistry and biology. As a chemist and molecular biologist, Liu is driven to understand, at a molecular level, how regulatory RNAs function. Using genetic and biochemical approaches, she has developed models for what is necessary and sufficient for gene regulation by certain small RNAs in bacteria. Her research findings inspire her to question how broadly applicable these functional models are, and this has led her to search out new examples of regulatory RNAs through screens and selections. Of course, leads identified in these studies must be characterized, and upon further investigation, she finds herself once again searching for molecular understanding. As a teacher-scholar, Liu is particularly invested in involving undergraduate students in her research program such that they can experience first hand the rewards and challenges of independent and collaborative science research.
Hosted by: Mark Wood and Patty Vest
Produced by: Jeff Hing
Transcript: https://www.pomona.edu/sites/default/files/sagecast-janeliu-040820.txt
Video Teaser: https://youtu.be/yR1hSKDnQ44
