Zach and Brandon discuss the evidence for and against using probiotics as treatment for medical diseases and the mechanisms that may confer health benefits to individuals without disease.
Subjective:
0:45 - Brandon’s experience at the Metabolic Health Summit
10:19 - Introduction to probiotics
21:38 - Zach and Brandon’s probiotic protocol for themselves
24:25 - Introduction to the microbiome
Objective:
32:25 - Probiotics as treatment and prevention for type II diabetes and obesity
45:08 - Treating digestive diseases with probiotics
55:20 - Using probiotics to treat and prevent allergic rhinitis and eczema
57:08 - Probiotics and depression
1:01:06 - Short-chain fatty acid (SCFA) effects on inflammation and innate immunity
1:18:00 - SCFAs and the gut-brain axis
1:24:34 - Insulin and satiety regulation through SCFAs
1:30:45 - Mitigating antibiotic side effects
1:32:30 - What to look for: strains, dosage, viability, timing
1:40:10 - Safety concerns and side effects
Assessment/Plan:
1:43:50 - Conclusion, using probiotics for treatment and healthy individuals
