Brandon and Zach share their experiences with intermittent fasting and discuss the physiology and potential as medical therapy.
Subjective:
0:58 - Catching up on clinical rotations and recent events
11:08 - Intermittent fasting definitions, terminology, and background
16:45 - Brandon and Zach’s personal fasting habits,
24:22 - What’s the “80/20” for eating and nutrition?
27:00 - The history of fasting across cultures
29:20 - What was the result of a 382-day fast?
Objective:
32:25 - Overview of fasting physiology: glucose regulation, ketone production, epinephrine, HGH
39:02 - Calorie-restriction v. intermittent fasting
42:45 - What breaks a fast?
44:55 - Autophagy and mTOR in fasting
Assessment/Plan:
49:40 - Risks and adverse side effects: hypoglycemia, orthorexia, refeeding syndrome
54:50 - Conclusion, future directions
People, Books, Podcasts Mentioned:
FoundMyFitness Podcast - Rhonda Patrick, Ph.D.
“Wired to Eat” Robb Wolf
Dr. Valter Longo, Ph.D.
Dr. Jason Fung, M.D.
Dr. Peter Attia, M.D.
