Join the insightful conversation in this episode with Dr. E.F. Rain and Dr. Stephanie Kullmann, Deputy Head of Metabolic Neuroimaging at the Institute for Diabetes Research and Metabolic Diseases (IDM), part of the Helmholtz Center Munich, University of Tübingen. Dr. Kullmann's research is dedicated to exploring neurobiological mechanisms related to obesity and diabetes in humans. Leveraging neuroimaging methods, particularly functional magnetic resonance imaging, and employing measures of peripheral metabolism, she is keen on assessing brain insulin action through intranasal insulin application. This approach allows for the investigation of the metabolic and cognitive consequences of brain insulin resistance.
In this talk, we delve into the concept of brain insulin sensitivity and unravel why understanding this aspect opens a new window for further research. Dr. Kullmann sheds light on how this exploration could be beneficial for the development of innovative treatments for individuals grappling with metabolic syndrome and obesity.
This episode was based in the following articles:
Reference: Kullmann S, Goj T, Veit R, Fritsche L, Wagner L, Schneeweiss P, Hoene M, Hoffmann C, Machann J, Niess A, Preissl H, Birkenfeld AL, Peter A, Häring HU, Fritsche A, Moller A, Weigert C, Heni M. Exercise restores brain insulin sensitivity in sedentary adults who are overweight and obese. JCI Insight. 2022 Sep 22;7(18):e161498. doi: 10.1172/jci.insight.161498. PMID: 36134657; PMCID: PMC9675563.
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Disclosure:
The content of this podcast is purely academic in nature and is intended for educational and informational purposes only. The material discussed does not represent or reflect the views, opinions, or policies of the Medical College of Georgia, and the information presented should not be construed as medical advice or guidance. Always consult with a qualified healthcare professional for any medical concerns or questions. I'd like to explicitly state that I have no endorsement from, affiliations with, or financial interests in any pharmaceutical companies or medical device manufacturers. Any mention of medications, devices, or treatments is made solely within the context of literature and academic discussion
