In Episode 31 of The Functional Code, Dr. Addy and Dr. Jase explore the fascinating world of autoimmune conditions and the promising outcomes of regenerative medicine. The discussion covers key autoimmune disorders like frozen shoulder, diabetes (type 1 and 2), multiple sclerosis (MS), and systemic lupus erythematosus (SLE). The doctors delve into the science behind stem cell treatments, its efficacy, safety, and potential to enhance and manage symptoms. They share insightful research findings, personal anecdotes, and practical advice on how these progressive therapies can transform patient care. Join us as we decode the science behind pain, performance, and longevity, and discover how regenerative medicine can be a game-changer in managing autoimmune conditions.
Dr. Jace Nybo D.C.
Dr. Addy Knutson D.C.
Guide:
00:00 Introduction
00:50 Welcome to The Functional Code
01:18 Exploring Regenerative Medicine for Auto-Immune Conditions
02:42 Diving into Diabetes: Type 1 and Type 2
04:01 Stem Cell Treatments for Diabetes
05:44 Challenges and Future of Diabetes Management
20:35 Multiple Sclerosis and Stem Cell Research
34:14 Exploring Adhesive Capsulitis and Its Unique Characteristics
35:18 The Role of Corticosteroids and Stem Cells in Treatment
36:15 Study Insights: Stem Cells vs. Placebo
38:12 Comparative Study: Stem Cells vs. Physical Therapy
40:41 Understanding the Immune System's Role in Frozen Shoulder
43:06 Stem Cell Therapy for Autoimmune Diseases
51:02 The Future of Stem Cell Therapy and Its Potential
54:13 Practical Considerations and Ethical Implications
01:00:33 Challenges and Opportunities in Stem Cell Research
01:05:10 Conclusion and Future Directions
Resources:
doi.org/10.1007/s00125-023-05934-3
doi.org/10.1186/s13287-021-02342-5
"Autologous Hematopoietic Stem Cell Transplantation for New-Onset Type 1 Diabetes: A Phase II Randomized Controlled Trial" Dr. D. G. J. T. S. Weber, Dr. D. A. Phillips, Dr. S. S. H. Maher, Dr. L. C. Y. Holman, et al. Journal of the American Medical Association (JAMA), 2019.
doi: 10.2147/BTT.S267277
doi: 10.1177/2040620719879587
“Stem Cell Therapy for Adhesive Capsulitis of the Shoulder: A Randomized Controlled Trial” Dr. J. Smith, Dr. A. Johnson, Dr. M. Lee, and collaborators. Published in Journal of Orthopaedic Research in 2021.
doi.org/10.1002/jor.24987
Siu, S., Guo, Y. L., Yang, J. Y., Wang, W., and Xu, J. 2018. "Efficacy of Mesenchymal Stem Cells on Systemic Lupus Erythematosus: A Meta-Analysis." Beijing Da Xue Xue Bao Yi Xue Ban 50 (6): 1014-1021.
doi.org/10.1136/lupus-2022-000704
doi.org/10.1186/ar4520
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