Dr. Nicholas Fabiano is a psychiatrist, researcher, and rising star in the world of mental health who’s challenging the foundations of how we diagnose and treat mental illness.
He believes depression isn’t just in your head — it’s in your whole body. From prescribing exercise as medicine to exploring the role of creatine in mood and cognition, Dr. Fabiano is pioneering a new, evidence-based psychiatry that breaks free from outdated diagnostic boxes and recognizes the deep connection between mental and physical health.
Expect to learn why the DSM fails to capture the complexity of depression, how exercise can match or exceed the effects of antidepressants, what creatine actually does in the brain, whether it could work as a standalone treatment, how psychiatry can benefit from AI and wearable data, why gait speed might predict IQ, whether cats really increase your risk of schizophrenia, and what it means to treat a person — not a label.
Plus, we dissect Dr. Fabiano’s most viral science threads, viewed by millions, and end with one big question:Could creatine save your personality?
Timestamps:
00:02:08 The Interconnection of Mental and Physical Health
00:04:59 Redefining Diagnostic Criteria in Mental Health
00:08:12 Challenges in Integrating Mental and Physical Health
00:11:15 The Role of AI in Diagnostics and Treatment
00:14:10 The Future of Prophylactic Care and Wearable Technology
00:17:08 The Importance of Exercise in Mental Health Treatment
00:31:09 The Importance of Proper Exercise Prescription
00:34:17 Reframing Exercise for Mental Health
00:40:23 Understanding the FIT Principle for Exercise
00:48:09 Creatine: A New Frontier in Mental Health
00:57:46 The Case for Universal Creatine Supplementation
01:00:06 Creatine and Sleep Deprivation
01:02:08 Creatine's Mechanism in Cognitive Function
01:04:06 Creatine and Depression: Exploring the Connection
01:05:57 Dietary Creatine and Mental Health
01:08:10 Forms of Creatine: What You Need to Know
01:10:04 Dosage and Timing of Creatine Supplementation
01:12:05 Creatine and Bipolar Disorder: A Cautionary Tale
01:14:03 Creatine's Role in Schizophrenia
01:18:15 Caffeine and Creatine: The Interaction
01:20:05 Exercise, Creatine, and Depression
01:22:04 Future Research Directions for Creatine
01:23:56 Creatine for Vegetarians and Vegans
01:29:47 Exploring the Efficacy of Creatine
01:30:14 Neuroscientific Insights on Emotional Bonds
01:32:28 Dietary Impacts on Brain Cancer Survival Rates
01:36:07 The Ketogenic Diet and Mental Health Applications
01:39:18 The Connection Between Pet Ownership and Mental Health
01:42:22 Coffee's Role in Aging and Cognitive Function
01:45:29 Daytime Napping and Brain Volume
01:47:55 Dog Ownership, Physical Activity, and Dementia Risk
01:49:57 Walking Speed as a Proxy for Cognitive Function
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Follow Dr Fabiano on X (He Posts Awesome Content) : https://x.com/NTFabianoCreatine as a treatment for depression: A brain bioenergetics perspective - https://pubmed.ncbi.nlm.nih.gov/40215588/
