What if you could measure your true biological age and predict your lifespan?
In this captivating episode of LiveLong, Livelong Media delves into the fascinating world of biological age with guest expert Irina Conboy, a professor of bioengineering at the University of California, Berkeley. The discussion unravels the mysteries surrounding biological age, debunks common misconceptions about aging clocks, and explores groundbreaking methods to measure and potentially slow down the aging process. Listeners will gain valuable insights into the latest research on longevity and learn about innovative approaches to understanding and quantifying health at a cellular level.
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[00:50:00 - 00:51:14] Decoding the Biological Clock: Understanding Age Beyond Numbers
- Biological age reflects the state of our cells, not just chronological years
- Knowing biological age can help predict lifespan and disease risk
- Researchers use various tools, including epigenetic clocks, to estimate biological age
[00:51:14 - 00:52:24] The Methylation Mirage: Why Popular Aging Clocks Fall Short
- DNA methylation patterns change with age but don't necessarily cause aging
- Most aging clocks predict chronological age, not biological age
- Current methods can't distinguish between correlation and causation in aging biomarkers
[00:52:24 - 00:53:12] Noise as the New Metric: Measuring Cellular Chaos
- Biological noise, or cell-to-cell variability, emerges as a true biomarker of aging
- The noise barometer concept measures the "pressure" of aging on an organism
- Higher biological noise correlates with increased aging and disease presence
[00:53:12 - 00:54:00] From Theory to Practice: Applying Biological Age Insights
- Arthritis patients show higher biological noise, indicating accelerated aging
- Measuring biological noise could enable early detection and prevention of diseases
- The car analogy: fixing cellular issues before they become major health problems
[00:54:00 - 00:55:00] The Future of Anti-Aging: Interventions and Implications
- Understanding biological age could lead to targeted anti-aging interventions
- Potential to reduce physiological age of specific organs or the entire body
- Treating aging as a "class" of conditions, similar to how antibiotics treat infections
Quotes:
"Biological age fundamentally answers an important question: How long have I got to live?" - John Beard, Ph.D.
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