This research investigates how plants defend against aphids using damage-associated molecular patterns (DAMPs), specifically oligogalacturonides (OGs). The study reveals that OGs trigger DAMP-triggered immunity (DTI) in Arabidopsis thaliana, limiting aphid colonization through key plant immune components like BAK1/BKK1, CPK5/6, GRP3, and EDS1. However, aphids counteract this defense by reducing OG production during feeding and deploying the salivary effector Mp10, which suppresses OG-induced DTI and interferes with pattern-triggered immunity (PTI) by affecting receptor stability in an EDS1-dependent manner. Notably, Mp10 also induces effector-triggered immunity (ETI), and in the absence of EDS1, it can unexpectedly restore plant responsiveness to OGs, highlighting a complex interplay between aphid effectors and plant immune signaling pathways.
Source: Aphid effector Mp10 balances immune suppression and defence activation through. Doi: https://doi.org/10.1101/2025.02.26.640334
