Paul Little is Professor of Primary Care Research at the University of Southampton. He is a Fellow of the Academy of Medial Sciences, a National Institute of Health Research (NIHR) Senior Investigator (emeritus), and winner of the Maurice Wood award (for Lifetime contribution to primary care research).
He led a wide range of studies in acute infections; diagnostic studies, prospective cohorts, placebo controlled trials, pragmatic trials of antibiotic prescribing strategies, and complex interventions to address antimicrobial stewardship and reduce the threat to public health of antibiotic resistance. His research has demonstrated reductions in antibiotic use in RTIs using: delayed antibiotic prescriptions; a clinical score for pharyngitis (FeverPAIN); communication skills training; C-reactive protein (CRP) point-of-care tests; and a digital intervention to support handwashing. This research has formed a key part of 9 national and 4 international guidelines, two UK 5-year AMR strategies and a successful intervention by the CMO for overprescribing GPs
