In the early evening of April 10, 1997 panic set in when Jeffrey Smith realized his wife wasn't where she was supposed to be. Having flown to Philadelphia for a conference, Jeffrey and his wife Judy were to attend a cocktail party in their hotel after a day of sightseeing for Judy and moderating for Jeffrey. Jeffrey had no idea that morning was actually the last time he'd ever see Judy again.
5 months later the scattered remains of Judy's body were found 600 miles south at a campground in Asheville, NC. Her disappearance and murder remain a mystery to this day.
Shoutout to Wendy for researching this story as one of the "most irritating disappearance" due to the fact that it's wildly unusual and still unsolved.
Sources:
Unsolved Mysteries
Wikipedia
