David Deutsch's The Beginning of Infinity explores the nature of knowledge and progress. The book argues that progress stems from creating and improving explanatory theories, not merely accumulating sensory experience, challenging empiricist views. Deutsch examines various misconceptions about knowledge, including justificationism and instrumentalism, and proposes fallibilism as a more accurate understanding. He discusses the importance of explanations in understanding the universe, from the workings of stars to the nature of human intelligence and the multiverse. Finally, the text explores the implications of these ideas for the future of humanity and the potential for continued progress.