In this episode of the Research Digest Podcast, we discussedthe article titled “Dynamic Changes in Heparan Sulfate Nanostructure in Human Pluripotent Stem Cell Differentiation”, published in ACS Nano (2023). We spoke with the lead author, Dr. Deena Al Mahbuba, about the background of the research work, its major findings, and future perspectives.
THIS EPISODE on YOUTUBE
https://youtu.be/rtVNZWDLmtU
ARTICLE LINK
https://pubs.acs.org/doi/full/10.1021/acsnano.2c10072
TIMESTAMPS
00:00 – Introduction
01:20 – Career journey of the author
04:45 – Introducing the author
05:30 – Starting the project and the knowledge gap
11:30 – Heparan sulfate proteoglycans and their importance
15:40 – Expansion microscopy
22:00 – Major findings and observations
32:00 – Role of heparan sulfate in the fate decision of hematopoietic stem cells
38:20 – Challenges of the project
43:40 – Message to the young scientists
