There's no doubt our fast-paced and frenetic lifestyle, coupled with a polluted environment, leaves us at the intersection of a perfect breeding ground for mental instability.
Your mental health is dependent upon a highly complex ecosystem of genetic, epigenetic, cellular, and microbiome-related influences.
And .. when it comes to supporting neurodiverse conditions and specifically (ADHD), we need a radically different approach—one that gets to its root cause, instead of relying solely on medication to suppress symptoms.
In this episode of the Awaken Beauty Podcast, I’m honored to have Dr. Greenblatt as we open up the discussion around the benefits that a Functional Medicine and Holistic Integrative approaches provide in addressing mental health and ADHD.
As many of my guests probably know, my history in Functional Medicine has brought me to the conclusion that the path and answers to our healthiest future reside in getting to the root.
Today’s episode explores the current state of genetics and mental health, and how to improve symptoms with safe, effective and proven nutritional and lifestyle interventions.
What You’ll Discover:
Research has established ADHD is a neurobiological condition & genetic
ADHD Brain Executive Function: Circuits in the frontal cortex of the brain are responsible for sustained attention, organization, planning, and various other executive functions are not functioning properly. In ADHD, the speed and efficiency of information processing is inconsistent, and compromised. These circuits mainly rely upon two neurotransmitters to function (dopamine and nor-epinephrine).
A bio- psycho- social approach - focuses on the environmental, psychological, and biological factors at play in a person’s life, and then developing a tailored multi-pronged approaches for support.
-The 4 root causes of ADHD Symptoms (genetic, neurological, nutritional and environmental)
The interrelated ecosystem of genetic, epigenetic, cellular, and microbiome-related influences.
-4 times more Adults being diagnosed with ADHD
-Burnout, as an ADHD woman, is not episodic, it’s a continuous state of being.
-Female ADHD traits can include an inability to keep time, feeling hypersensitive to rejection, emotional dysregulation, trouble maintaining friendships, binge eating, overspending and experiencing imposter syndrome. Almost universally, women report low self-esteem.
- What role hormones play in women with ADHD
-Enzymatic COMT Genetic markers to better understand Dopamine production / lack thereof.
The “Stress Response Gene”
The COMT gene produces an enzyme that determines whether you are a “worrier” or a “warrior”
If your gene has a variation that produces more of the COMT enzyme, you’re naturally equipped to perform well in high-stress situations—however, your executive function in normal circumstances is not quite as good.
MTHFR: Methylfolate is used to make brain chemicals essential for a number of aspects of our mental health—including the neurotransmitters serotonin, dopamine, and norepinephrine. Without enough methylfolate, these neurotransmitter levels decrease, leading to—among other things—depression and anxiety
-The key tenets of Functional and Integrative Medicine as they apply to mental illness, and benefits of nutritional supplementation
-Nutritional deficiencies and food allergies
- Biochemical individuality by testing serum B12, homocysteine levels and folate
Antibiotic use, esp under 6 tied to cognitive issues in later years
Mg is the best supplement for ADHD.. lithium, zinc.. high copper seen in ADHD
Lithium Orotate 1-2 mg titrate up to 5mg.. different from Lithium Rx.
Mold can be an underlying factor in adults… not so much in kids
-Folic Acid: High levels ofThe folic acid in the blood can block receptors in the bloodbrain barriers.
Compt gene worries versus warrior theory
COMT is a key enzyme in the elimination of dopamine. A Val/Val gene has increased COMT activity, which leads to lower dopamine levels and relatively lower prefrontal cognitive function than in individuals with Met/Met Genes.
-Supplements like Green tea extract slows down the compt enzyme reduction of dopamine
-Issues are exacerbated by fungal toxins linked to chronic candidiasis and mold produced compounds.
-Lithium a wonder element? Long-term lithium treatment increases intracellular and extracellular brain-derived neurotrophic factor (BDNF) in cortical and hippocampal neurons at subtherapeutic concentrations.
-Lithium has been found to support alzthiemers and just 1 to 2 MG helps ADHD kids.
-How to test for genetics and accurate supplementation.
-Psychedelics
-OAT Test: To measure the gut and yeast.
-IGG Allergy Test
-Gut Microbiome and we can detect the dopamine metabolism - and when treating the gut, we can address the hyperactivity.
About Dr James Greeblatt
A pioneer in the field of integrative medicine, Dr. James Greenblatt has treated patients since 1988.
Hes an acknowledged integrative medicine expert, educator, and author, and he has lectured internationally on the scientific evidence for nutritional interventions in psychiatry and mental illness.
In April of 2017, Dr. Greenblatt was inducted into the Orthomolecular Medicine Hall of Fame and has lectured internationally on the scientific evidence for nutritional interventions in psychiatry and mental illness, and as the author of seven books, including Finally Focused: The Breakthrough Natural Treatment Plan for ADHD.
Lastly, he is the founder of Psychiatry Redefined, an educational platform dedicated to the transformation of psychiatry full of CE-approved courses, webinars, and fellowships for professionals about functional and integrative medicine to resolve the concerns of modern day mental illness.
Resource: https://www.psychiatryredefined.org/
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