Join us as we investigate the metabolic theory of Alzheimer’s disease, which posits that the brain struggles to utilize its primary energy source, glucose. We explore how Medium Chain Triglycerides (MCTs)—found in sources like coconut oil and the medical food Axona—are metabolized into ketones to serve as an alternative “backup” fuel for starving neurons. This episode examines the dramatic anecdotal reports championed by Dr. Mary Newport, whose husband experienced significant cognitive improvements after taking coconut oil, sparking global interest and hundreds of caregiver testimonials.
However, the science is complex and contested. We analyze systematic reviews and meta-analyses indicating that while MCTs may improve general cognitive function, the benefits might be limited to individuals without the APOE4 gene variant. We also navigate the heated debate surrounding safety, contrasting claims of cognitive restoration with warnings from experts who label coconut oil “pure poison” due to its high saturated fat content. Finally, we look beyond memory to preclinical research suggesting MCT-supplemented diets may reduce anxiety and improve social competitiveness.Thanks to Keppi MCT
