The cybersecurity landscape is moving to an AI-vs-AI world where both attackers and defenders can operate at machine speed.
In this conversation, Anne Neuberger and Sam Jones join Jai Ramaswamy to go deeper on what this shift looks like in practice. Neuberger draws on nearly two decades in government—including serving as deputy national security advisor for cyber and emerging technology—to explain how AI is transforming the threat landscape, most notably making attacks faster, cheaper, and continuous at scale. Jones brings the builder’s perspective as CEO and cofounder of Method Security, where his team is building autonomous cyber systems for both offense and defense observing firsthand how AI is accelerating everything from routine tactics to exploit development.
Together, they discuss what “cyber resilience” means in an AI world: continuous testing and red-teaming that was previously cost-prohibitive, clearer benchmarks for critical infrastructure, and faster recovery when disruptions happen.
They also walk through the policy measures that can help defenders keep pace.
Topics covered:
03:16: How AI changes the threat landscape
07:38: Net new risks in an AI-vs-AI cyber world
11:21: Building trust to deploy new technology in no-fail systems13:55: Cybercrime at machine speed
17:18: Who benefits more from AI: attackers or defenders?1
9:29: Tactics to remove friction for defenders
22:26: Real examples of incidents where AI could have changed outcomes: Colonial Pipeline and Change Healthcare
27:18: What cyber resilience means in an AI world30:57: Measuring resilience
36:59: Information sharing and antitrust: lessons from financial services and telecom compromises
44:59: The builder’s view: what Method Security is building for offense + defense
49:27: Little Tech realities of building with a small team and selling into government
52:53: The role of procurement in ensuring defensive systems keep pace with adversaries
55:32: What’s next: in-year buying flexibility and closing thoughts
Resources:
Subscribe to the a16z AI Policy Brief: https://a16zpolicy.substack.com/
Follow Jai Ramaswamy: https://www.linkedin.com/in/jai-ramaswamy-85a77675/
Follow Anne Neuberger: https://www.linkedin.com/in/anne-neuberger-13b4491b/
Follow Sam Jones: @___sjones
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