In the episode we will cover the following learning objectives:



·       Listeners should be able to describe the evolution and changes in definitions sepsis over the past three decades

·       Listeners should be familiar with the three randomized controlled trials that studies early-goal directed therapy

·       Listeners should be able to describe the major changes in the new 2021 SCCM Sepsis Guidelines

·       Listeners should be able to describe the fundamental principles of sepsis management in the ICU



References:



https://www.nejm.org/doi/full/10.1056/nejmoa1500896



https://www.nejm.org/doi/full/10.1056/nejmoa1404380



https://www.nejm.org/doi/full/10.1056/nejmoa1701380



https://www.nejm.org/doi/full/10.1056/nejmoa1401602



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