π¨ New Study Alert! π§ π§ͺ
How does your brain handle a blocked drain β and does age make it worse? π€π§
This podcast dives into how chronic impairment of deep cervical lymphatic drainage affects brain fluid dynamics and triggers low-grade neuroinflammation β all in an age-dependent manner. π§βοΈπΆ
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π Using DCE-MRI, proteomics, and metabolomics, we found that:
β Young brains adapt with increased clearance and extracranial drainage
β οΈ Middle-aged brains show blunted responses and molecular signs of stress
𧬠Both age groups reveal early markers of neurodegeneration and BBB leakage
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π Read the full study in JCI
#Neuroscience #GlymphaticSystem #Lymphatics #BrainHealth #Aging #MRI #Neuroinflammation #TranslationalResearch #CSF #PrecisionMedicineΒ