The SOUL trial ๐งช showed that oral semaglutide ๐ significantly reduced major cardiovascular events โค๏ธ (MACE) in people with type 2 diabetes ๐ฉธ and ASCVD/CKD ๐.
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Over ~4 years, it cut heart attacks ๐ฅ, lowered HbA1c ๐, reduced weight โ๏ธ, and inflammation ๐ฅ โ all with a once-daily pill ๐๏ธ and no rise in serious side effects.