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Our July 2012 podcast highlights a paper published by Dr. Valdimir Pech and his colleagues entitled “ENaC inhibition stimulates Cl- secretion in the mouse cortical collecting duct through an NKCC1-dependent mechanism”. Join us as Editor-in-Chief Thomas Kleyman and Vladimir Pech discuss  the role of electrogenic Na+ absorption in Cl- absorption, and how Dr. Pech's work contrasts with previous studies addressing Cl- absorption in the CCD.

Vladimir Pech, Monika Thumova, Young Hee Kim, Diana Agazatian, Edith Hummler, Bernard C. Rossier, Alan M. Weinstein, Masayoshi Nanami, and Susan M. Wall.ENaC inhibition stimulates Cl− secretion in the mouse cortical collecting duct through an NKCC1-dependent mechanisn. Am J Physiol Renal Physiol July 1, 2012 303:F45-F55; published ahead of print April 11, 2012, doi:10.1152/ajprenal.00030.2012