In this revealing episode of "Cracking Cancer," host Dr. Kyle Concannon and co-host Samantha Murrell are joined by Kerry Wentworth, Chief Regulatory Officer at Nuvation Bio, to pull back the curtain on the pharmaceutical and biotech industry. Kerry, a veteran in the field, addresses the common perception that pharmaceutical companies are driven purely by financial metrics, stating that the primary mission is, in fact, patient-centered—to bring healthier, longer living to people.
The conversation dives deep into the high-risk reality of drug development. Kerry explains why drugs cost billions: the price must account for the staggering 90% failure rate of investigational new drugs, extensive animal and human trials, and complex manufacturing. They demystify the clinical trial process, clarifying the phases, the rigorous site selection process, and dispelling the myth that physicians receive financial kickbacks for enrolling patients. This episode is a must-listen for anyone who wants an honest, science-driven understanding of the dedication, cost, and high-stakes nature of the work required to bring a new cancer therapy to market.
Key Takeaways
Chapters
(00:00) Understanding the Pharmaceutical Industry
(08:08) The Role of a Chief Regulatory Officer
(11:55) The Drug Development Process
(17:19) Clinical Trials: Design and Execution
(26:10) Phase One Trials and FDA Approval
(35:15) Understanding Investigator Payments
(42:16) Challenges in Cancer Vaccine Development
(49:41) Mistrust in Pharmaceutical Companies
(59:08) New Developments at Nueva Bio
The Cracking Cancer Podcast's main focus is to further education about cancer and its effects on people and communities through continued discussion and to raise funds for the continued research of cancer treatments and positive outcomes. All raised proceeds go directly to the continued upkeep of this podcast and cancer research. To find out more about supporting the show and research endeavors, please go to the following website: www.crackingcancer.org
Attributions
The music track - Progression Pulse - is provided by Denys Brodovskyi through the Attribution 4.0 International License
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