Tight28 starts July 6 — only offered once a year in LIVE format.
This isn’t a gut reset or an elimination diet. It’s a discovery program for anyone who knows they don’t feel as great as they could. Join now → WWW.TIGHT28.COM
💥 Episode Overview:
In this episode, Joanne takes a deep dive into a topic that's rarely discussed but highly impactful: histamine intolerance. Often mistaken for allergies or hormone issues, histamine overload can be the hidden cause behind bloating, anxiety, brain fog, poor sleep, and even body composition challenges.
This episode is rich with information—even if you don’t listen, the notes below will give you a full understanding of:
What histamine is and why your body needs it
What causes histamine intolerance (spoiler: it’s not just about food)
Why midlife women and men are particularly vulnerable
How histamine can derail your sleep, hormones, and fat loss
What foods to watch for (and why some “healthy” ones might be causing symptoms)
How to support your body’s ability to clear histamine and feel better fast
🧪 What Is Histamine?
Histamine is a naturally occurring compound in your body, essential for:
Regulating stomach acid
Acting as a neurotransmitter for alertness
Supporting the immune system’s defense mechanisms
Histamine isn’t bad—but too much of it with too little clearance leads to histamine intolerance.
Histamine intolerance = Buildup > Breakdown
🔍 What Causes Histamine Intolerance?
The key enzyme that breaks histamine down is DAO (diamine oxidase)—and it’s made in your gut lining.
If your gut is inflamed, leaky, or imbalanced (which it likely is if you’re eating processed foods or have high stress), DAO levels drop. Add in some high-histamine foods or DAO-blocking substances, and boom—you’re suddenly reacting to foods you used to tolerate just fine.
🚨 Common Symptoms of Histamine Intolerance
Flushed or red face after meals
Headaches, migraines
Nasal congestion, postnasal drip
Itchy skin or unexplained rashes
Anxiety or panic after eating
Dizziness or rapid heartbeat
Bloating, water retention
PMS or worsened menopause symptoms
Intolerance to wine or fermented foods
Sound familiar? It often gets misdiagnosed as a hormone imbalance, allergy, or “just getting older.”
🧬 Why Midlife Women and Men Struggle More
Midlife Women:
Estrogen increases histamine release and suppresses DAO.
Women on HRT may suddenly experience itchy rashes or anxiety and blame estrogen—when histamine overload is the real issue.
DAO supplementation and gut support can allow HRT to work better without side effects.
Midlife Men:
Declining testosterone + rising visceral fat = higher inflammation.
This inflammation weakens the gut, decreases DAO, and worsens histamine sensitivity.
Restoring gut integrity + using DAO support = less bloating, better energy, clearer mind.
🧰 What You Can Do About It
Short-Term Fix:
Try a low-histamine diet for 1–2 weeks.
Focus on fresh-cooked, non-fermented meals.
Avoid leftovers and “healthy” foods like avocado, spinach, or sauerkraut temporarily.
Support DAO Production:
Nutrients: Vitamin C, B6, copper, magnesium
DAO-Supportive Foods: Pea sprouts, mung beans, arugula, watercress
DAO Supplements: Look for porcine kidney extract (take 15–30 mins before meals)
Heal the Gut:
Glutamine, collagen, zinc carnosine, bone broth
Support detox: Glutathione, NAC, milk thistle, broccoli sprouts
Use probiotics that don’t promote histamine-producing bacteria
🎯 How It Impacts Body Composition
Poor sleep = impaired fat-burning hormones (growth hormone, testosterone)
Increased estrogen dominance = more fat storage, less muscle tone
Inflammation = bloating, water retention, digestive distress
Dysregulated appetite = cravings, over-snacking, stubborn belly fat
💬 Final Thoughts
Histamine intolerance is a hidden disruptor—and most people never realize it. That mystery bloating? Restless sleep? Feeling anxious after a glass of wine? It might not be your hormones or aging. It might be your histamine load.
You don’t need to cut everything out forever—just support your system, heal your gut, reduce the overload, and reintroduce foods with clarity and confidence.
🎓 Join Tight28 – Starts July 6
Tight28 isn’t about restriction. It’s about discovery.
In this one-of-a-kind 4-week coaching program, we explore:
Histamine intolerance
Enzyme function & absorption
Leaky gut & LPS
Cross-reactivity (gluten, dairy, soy)
Gut-brain-skin axis
Estrogen & gut motility
Appetite, food sensitivities, inflammation, and more
You’ll walk away with clarity, tools, and a completely new understanding of how your body actually works.
Only offered LIVE once a year. Join us here → www.tight28.com July 6 - August 2
