Explore Harlequin Syndrome — differential hypoxemia seen in peripheral VA-ECMO and complex cardiopulmonary bypass cases — in this in-depth perfusion podcast. We define the hemodynamic and respiratory mechanisms behind the syndrome, review monitoring cues, and outline evidence-based approaches to diagnosis and correction. Designed for perfusionists, intensivists, and ECMO teams seeking clarity on a nuanced but critical clinical issue.
