In this focused medical education podcast, we break down the use of methylene blue as an adjunct vasopressor in critical care. Known for its role in vasoplegic shock and nitric oxide inhibition, methylene blue has unique effects on vascular tone that can support refractory hypotension when traditional agents fail.
📌 In this podcast, you'll learn: What is methylene blue and how does it work? Mechanism of action: nitric oxide pathway inhibition, guanylate cyclase blockade Receptor-independent vasopressor effects Clinical indications: vasoplegia, catecholamine-refractory shock, post-cardiac surgery hypotension Dosing strategies and administration considerations Common and serious side effects (serotonin syndrome, MAOI interactions, hemolysis in G6PD) Summary of key clinical evidence and controversies Board-style practice questions at the end 🎯 Perfect for learners preparing for USMLE, Step 2/3, critical care boards, or managing refractory shock in the ICU or OR.
📚 Related Resources: Download our Methylene Blue study guide and practice questions: https://www.patreon.com/collection/1443765
Watch next: Playlist Vasopressors and Inotropes: https://youtube.com/playlist?list=PLf5bMa9_tvRg_nAnm91hsyHhI0y_ahoS1&si=Myz25vHJgHAp4Nvc
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